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Immunotherapy of tuberculosis with Mycobacterium leprae Hsp65 as a DNA vaccine triggers cross-reactive antibodies against mammalian Hsp60 but not pathological autoimmunity.
Doimo, Nayara T S; Zárate-Bladés, Carlos R; Rodrigues, Rodrigo F; Tefé-Silva, Cristiane; Trotte, Marcele N S; Souza, Patrícia R M; Soares, Luana S; Rios, Wendy M; Floriano, Elaine M; Brandão, Izaira T; Masson, Ana P; Coelho, Verônica; Ramos, Simone G; Silva, Celio L.
Affiliation
  • Doimo NT; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Zárate-Bladés CR; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Rodrigues RF; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Tefé-Silva C; Department of Pathology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Trotte MN; Veterinary Medical Department of Anatomical Pathology; State University of Rio de Janeiro; Rio de Janeiro, Brazil.
  • Souza PR; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Soares LS; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Rios WM; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Floriano EM; Department of Pathology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Brandão IT; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Masson AP; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Coelho V; Laboratory of Immunology; Heart Institute (InCor); School of Medicine; University of São Paulo; São Paulo, Brazil; Institute for Investigation in Immunology (iii)-National Institute of Science and Technology; São Paulo, Brazil.
  • Ramos SG; Department of Pathology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
  • Silva CL; The Centre for Tuberculosis Research; Department of Biochemistry and Immunology; Ribeirão Preto School of Medicine; University of São Paulo; São Paulo, Brazil.
Hum Vaccin Immunother ; 10(5): 1238-43, 2014.
Article in En | MEDLINE | ID: mdl-24607935
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Autoimmunity / Chaperonin 60 / Vaccines, DNA / Mitochondrial Proteins / Antibodies, Bacterial / Mycobacterium leprae Limits: Animals Language: En Journal: Hum Vaccin Immunother Year: 2014 Document type: Article Affiliation country: Brazil Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Autoimmunity / Chaperonin 60 / Vaccines, DNA / Mitochondrial Proteins / Antibodies, Bacterial / Mycobacterium leprae Limits: Animals Language: En Journal: Hum Vaccin Immunother Year: 2014 Document type: Article Affiliation country: Brazil Country of publication: United States