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Alkylsulfone-containing trisubstituted cyclohexanes as potent and bioavailable chemokine receptor 2 (CCR2) antagonists.
Cherney, Robert J; Mo, Ruowei; Yang, Michael G; Xiao, Zili; Zhao, Qihong; Mandlekar, Sandhya; Cvijic, Mary Ellen; Charo, Israel F; Barrish, Joel C; Decicco, Carl P; Carter, Percy H.
Affiliation
  • Cherney RJ; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States. Electronic address: robert.cherney@bms.com.
  • Mo R; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Yang MG; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Xiao Z; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Zhao Q; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Mandlekar S; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Cvijic ME; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Charo IF; Gladstone Institute of Cardiovascular Disease, J David Gladstone Research Institutes, San Francisco, CA 94158, United States.
  • Barrish JC; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Decicco CP; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
  • Carter PH; Research and Development, Bristol-Myers Squibb Company, Princeton, NJ 08543-4000, United States.
Bioorg Med Chem Lett ; 24(7): 1843-5, 2014 Apr 01.
Article in En | MEDLINE | ID: mdl-24613378
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Receptors, CCR2 Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfones / Receptors, CCR2 Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Document type: Article Country of publication: United kingdom