Ca++-sensitizing mutations in troponin, P(i), and 2-deoxyATP alter the depressive effect of acidosis on regulated thin-filament velocity.

Longyear, Thomas J; Turner, Matthew A; Davis, Jonathan P; Lopez, Joseph; Biesiadecki, Brandon; Debold, Edward P

Longyear, Thomas J; Turner, Matthew A; Davis, Jonathan P; Lopez, Joseph; Biesiadecki, Brandon; Debold, Edward P.

Affiliation

Longyear TJ; Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts;

J Appl Physiol (1985) ; 116(9): 1165-74, 2014 May 01.

Article in En | MEDLINE | ID: mdl-24651988

Subject(s)

Acidosis/genetics; Calcium/metabolism; Deoxyadenine Nucleotides/genetics; Mutation/genetics; Phosphates/physiology; Troponin/genetics; Acidosis/metabolism; Actins/chemistry; Actins/genetics; Amino Acid Sequence; Animals; Chickens; Deoxyadenine Nucleotides/chemistry; Humans; Molecular Sequence Data; Myosins/chemistry; Myosins/genetics; Protein Structure, Secondary; Rabbits; Troponin/chemistry

Key words

2-deoxy-ATP; fatigue; phosphate; regulation; troponin C; troponin I

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphates / Acidosis / Troponin / Calcium / Deoxyadenine Nucleotides / Mutation Limits: Animals / Humans Language: En Journal: J Appl Physiol (1985) Journal subject: FISIOLOGIA Year: 2014 Document type: Article

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