Alternative splicing governs cone cyclic nucleotide-gated (CNG) channel sensitivity to regulation by phosphoinositides.

Dai, Gucan; Sherpa, Tshering; Varnum, Michael D

Dai, Gucan; Sherpa, Tshering; Varnum, Michael D.

Affiliation

Dai G; From the Department of Integrative Physiology and Neuroscience.

J Biol Chem ; 289(19): 13680-90, 2014 May 09.

Article in En | MEDLINE | ID: mdl-24675082

Subject(s)

Alternative Splicing/physiology; Cyclic Nucleotide-Gated Cation Channels/metabolism; Exons; Eye Proteins/metabolism; Phosphatidylinositol 4,5-Diphosphate/metabolism; Phosphatidylinositol Phosphates/metabolism; Retinal Cone Photoreceptor Cells/metabolism; Animals; Cyclic Nucleotide-Gated Cation Channels/genetics; Dogs; Evolution, Molecular; Eye Proteins/genetics; Female; Humans; Male; Phosphatidylinositol 4,5-Diphosphate/genetics; Phosphatidylinositol Phosphates/genetics; Protein Isoforms/genetics; Protein Isoforms/metabolism; Retinal Cone Photoreceptor Cells/cytology

Key words

Allosteric Regulation; Alternative Splicing; Ion Channels; Phosphoinositides; Photoreceptors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Exons / Alternative Splicing / Phosphatidylinositol Phosphates / Retinal Cone Photoreceptor Cells / Phosphatidylinositol 4,5-Diphosphate / Eye Proteins / Cyclic Nucleotide-Gated Cation Channels Type of study: Diagnostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Biol Chem Year: 2014 Document type: Article Country of publication: United States

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