Povidone iodine in the treatment of adenoviral conjunctivitis in infants.
Cutan Ocul Toxicol
; 34(1): 12-5, 2015 Mar.
Article
in En
| MEDLINE
| ID: mdl-24678746
ABSTRACT
CONTEXT Adenoviral conjunctivitis. OBJECTIVE:
To examine the effects of conjunctival irrigation with povidone iodine in infants with adenoviral conjunctivitis. MATERIAL ANDMETHODS:
An outbreak of adenovirus conjunctivitis occurred between September and December 2012 at the neonatal intensive care unit of our hospital. Forty-three infants with adenoviral conjunctivitis were examined in this study. Thirty-five eyes of 35 infants who had detailed ophthalmological examination and clinical scoring were included. The conjunctiva of 15 infants (Group 1) were irrigated with povidone iodine 2.5% solution and then treated with preservative-free artificial tears and preservative-free antibiotic drops. Twenty infants (Group 2) were treated only with the same drops with the same posology, without conjunctival irrigation with povidone iodine. Patients were examined two times a week until the complete recovery. Lid edema, conjunctival chemosis, fragility of conjunctival vasculature, pseudomembrane formation, and corneal involvement were scored clinically.RESULTS:
Twenty patients (57%) were female and 15 patients (43%) were male and mean age was 3.1 months (ranged from 1 to 4 months). No relation was found between gender and clinical scores. Statistically significant lower clinical scores were obtained from Group 1. The median recovery time was earlier in Group 1 (7 d) than Group 2 (12 d) (p = 0.001).CONCLUSION:
Conjunctival irrigation with 2.5% povidone iodine is effective in the treatment of adenoviral conjunctivitis in infants.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Povidone-Iodine
/
Conjunctivitis, Viral
/
Cross Infection
/
Adenoviridae Infections
/
Anti-Infective Agents, Local
Limits:
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Cutan Ocul Toxicol
Journal subject:
DERMATOLOGIA
/
OFTALMOLOGIA
/
TOXICOLOGIA
Year:
2015
Document type:
Article