Privileged phosphine-based metal-organic frameworks for broad-scope asymmetric catalysis.
J Am Chem Soc
; 136(14): 5213-6, 2014 Apr 09.
Article
in En
| MEDLINE
| ID: mdl-24684238
ABSTRACT
A robust and porous Zr metal-organic framework (MOF) based on a BINAP-derived dicarboxylate linker, BINAP-MOF, was synthesized and post-synthetically metalated with Ru and Rh complexes to afford highly enantioselective catalysts for important organic transformations. The Rh-functionalized MOF is not only highly enantioselective (up to >99% ee) but also 3 times as active as the homogeneous control. XAFS studies revealed that the Ru-functionalized MOF contains Ru-BINAP precatalysts with the same coordination environment as the homogeneous Ru complex. The post-synthetically metalated BINAP-MOFs provide a versatile family of single-site solid catalysts for catalyzing a broad scope of asymmetric organic transformations, including addition of aryl and alkyl groups to α,ß-unsaturated ketones and hydrogenation of substituted alkene and carbonyl compounds.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Am Chem Soc
Year:
2014
Document type:
Article
Affiliation country:
United States