Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa.

Barbonetti, A; Vassallo, M R C; Costanzo, M; Battista, N; Maccarrone, M; Francavilla, S; Francavilla, F

Barbonetti, A; Vassallo, M R C; Costanzo, M; Battista, N; Maccarrone, M; Francavilla, S; Francavilla, F.

Affiliation

Barbonetti A; Andrology Unit, Department of Life, Health and Environment Sciences, University of L'Aquila, L'Aquila, Italy; San Raffaele Sulmona Institute, Sulmona, Italy.

Andrology ; 2(4): 502-9, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24692267

Subject(s)

Lipopolysaccharides/pharmacology; Membrane Potential, Mitochondrial/drug effects; Receptor, Cannabinoid, CB1/physiology; Spermatozoa/drug effects; 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine/analogs & derivatives; Deoxyguanosine/metabolism; Humans; Male; Mitochondria/metabolism; Reactive Oxygen Species/metabolism; Sperm Motility/drug effects; Sperm Motility/physiology; Spermatozoa/metabolism

Key words

CB1 receptor; E. coli lipopolysaccharide; endocannabinoids; human spermatozoa; mitochondrial membrane potential

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spermatozoa / Lipopolysaccharides / Receptor, Cannabinoid, CB1 / Membrane Potential, Mitochondrial Type of study: Prognostic_studies Limits: Humans / Male Language: En Journal: Andrology Year: 2014 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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