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Electrophysiological profile of vernakalant in an experimental whole-heart model: the absence of proarrhythmia despite significant effect on myocardial repolarization.
Frommeyer, Gerrit; Milberg, Peter; Clauss, Catharina; Schmidt, Marco; Ramtin, Shahram; Kaese, Sven; Grundmann, Fabian; Grotthoff, Jochen Schulze; Pott, Christian; Eckardt, Lars.
Affiliation
  • Frommeyer G; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany gerrit.frommeyer@ukmuenster.de.
  • Milberg P; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Clauss C; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Schmidt M; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Ramtin S; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Kaese S; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Grundmann F; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Grotthoff JS; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Pott C; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
  • Eckardt L; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, 48149 Münster, Germany.
Europace ; 16(8): 1240-8, 2014 Aug.
Article in En | MEDLINE | ID: mdl-24696223
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arrhythmias, Cardiac / Pyrrolidines / Electrophysiologic Techniques, Cardiac / Heart Conduction System / Anisoles / Anti-Arrhythmia Agents Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Europace Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2014 Document type: Article Affiliation country: Germany Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arrhythmias, Cardiac / Pyrrolidines / Electrophysiologic Techniques, Cardiac / Heart Conduction System / Anisoles / Anti-Arrhythmia Agents Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Europace Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2014 Document type: Article Affiliation country: Germany Country of publication: United kingdom