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Neuroprotective effects of the andrographolide analogue AL-1 in the MPP⁺/MPTP-induced Parkinson's disease model in vitro and in mice.
Zhang, Zaijun; Lai, Daoxu; Wang, Liang; Yu, Pei; Zhu, Longjun; Guo, Baojian; Xu, Lipeng; Zhou, Libing; Sun, Yewei; Lee, Simon Ming Yuen; Wang, Yuqiang.
Affiliation
  • Zhang Z; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
  • Lai D; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
  • Wang L; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Avenue Padre Tomás Pereira S.J., Macao SAR, China.
  • Yu P; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
  • Zhu L; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
  • Guo B; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
  • Xu L; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
  • Zhou L; Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou 510632, China.
  • Sun Y; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China. Electronic address: syw1984@163.com.
  • Lee SM; State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Avenue Padre Tomás Pereira S.J., Macao SAR, China. Electronic address: simonlee@umac.mo.
  • Wang Y; Institute of New Drug Research and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine, Jinan University College of Pharmacy, Guangzhou 510632, China.
Pharmacol Biochem Behav ; 122: 191-202, 2014 Jul.
Article in En | MEDLINE | ID: mdl-24726706
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease, Secondary / Pyrans / Spiro Compounds / Neuroprotective Agents / MPTP Poisoning / Disease Models, Animal / Diterpenes Limits: Animals / Humans / Male Language: En Journal: Pharmacol Biochem Behav Year: 2014 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease, Secondary / Pyrans / Spiro Compounds / Neuroprotective Agents / MPTP Poisoning / Disease Models, Animal / Diterpenes Limits: Animals / Humans / Male Language: En Journal: Pharmacol Biochem Behav Year: 2014 Document type: Article Affiliation country: China Country of publication: United States