Eosinophilia in mast cell disease.

Kovalszki, Anna; Weller, Peter F

Kovalszki, Anna; Weller, Peter F.

Affiliation

Kovalszki A; Division of Allergy and Inflammation, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA. Electronic address: akovalsz@bidmc.harvard.edu.
Weller PF; Division of Allergy and Inflammation, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue CLS943, Boston, MA 02215, USA; Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue CLS943, Boston, MA 02215, USA.

Immunol Allergy Clin North Am ; 34(2): 357-64, 2014 May.

Article in En | MEDLINE | ID: mdl-24745679

Subject(s)

Eosinophils/pathology; Gene Expression Regulation, Neoplastic; Hypereosinophilic Syndrome/pathology; Mast Cells/pathology; Mastocytosis, Systemic/pathology; Antineoplastic Agents/therapeutic use; Benzamides/therapeutic use; Bone Marrow/drug effects; Bone Marrow/metabolism; Bone Marrow/pathology; Cell Communication; Eosinophils/drug effects; Eosinophils/metabolism; Humans; Hypereosinophilic Syndrome/drug therapy; Hypereosinophilic Syndrome/genetics; Hypereosinophilic Syndrome/metabolism; Imatinib Mesylate; Mast Cells/drug effects; Mast Cells/metabolism; Mastocytosis, Systemic/drug therapy; Mastocytosis, Systemic/genetics; Mastocytosis, Systemic/metabolism; Oncogene Proteins, Fusion/genetics; Oncogene Proteins, Fusion/metabolism; Piperazines/therapeutic use; Protein Kinase Inhibitors/therapeutic use; Proto-Oncogene Proteins c-kit/genetics; Proto-Oncogene Proteins c-kit/metabolism; Pyrimidines/therapeutic use; Receptor, Platelet-Derived Growth Factor alpha/genetics; Receptor, Platelet-Derived Growth Factor alpha/metabolism; Signal Transduction; Stem Cell Factor/genetics; Stem Cell Factor/metabolism; mRNA Cleavage and Polyadenylation Factors/genetics; mRNA Cleavage and Polyadenylation Factors/metabolism

Key words

Chronic eosinophilic leukemia (CEL); Eosinophilia; FIP1L1-PDGFRA fusion; Hypereosinophilic syndrome; Imatinib; Systemic mastocytosis; Tryptase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Hypereosinophilic Syndrome / Mastocytosis, Systemic / Eosinophils / Mast Cells Language: En Journal: Immunol Allergy Clin North Am Journal subject: ALERGIA E IMUNOLOGIA Year: 2014 Document type: Article

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