Terminal hypothermic Tau.P301L mice have increased Tau phosphorylation independently of glycogen synthase kinase 3&#945;/ß.

Maurin, Hervé; Lechat, Benoit; Borghgraef, Peter; Devijver, Herman; Jaworski, Tomasz; Van Leuven, Fred

Terminal hypothermic Tau.P301L mice have increased Tau phosphorylation independently of glycogen synthase kinase 3α/ß.

Maurin, Hervé; Lechat, Benoit; Borghgraef, Peter; Devijver, Herman; Jaworski, Tomasz; Van Leuven, Fred.

Affiliation

Maurin H; Experimental Genetics Group LEGTEGG, Department of Human Genetics, KU Leuven, Campus Gasthuisberg ON1 06.602, Herestraat 49, B-3000, Leuven, Belgium.

Eur J Neurosci ; 40(2): 2442-53, 2014 Jul.

Article in En | MEDLINE | ID: mdl-24754737

Subject(s)

Glycogen Synthase Kinase 3/metabolism; Protein Processing, Post-Translational; Tauopathies/metabolism; tau Proteins/metabolism; Animals; Glycogen Synthase Kinase 3/genetics; Humans; Hypothermia/metabolism; Hypothermia/physiopathology; Mice; Neurons/metabolism; Phosphorylation; Prosencephalon/cytology; Prosencephalon/metabolism; Prosencephalon/pathology; Protein Subunits/genetics; Protein Subunits/metabolism; Tauopathies/physiopathology; tau Proteins/genetics; tau Proteins/toxicity

Key words

body temperature; neurodegeneration; precocious death; tauopathy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Processing, Post-Translational / Tau Proteins / Tauopathies / Glycogen Synthase Kinase 3 Limits: Animals / Humans Language: En Journal: Eur J Neurosci Journal subject: NEUROLOGIA Year: 2014 Document type: Article Affiliation country: Belgium Country of publication: France

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