Structural signs of dynamic state of synaptic contacts between neurotransplant and brain.
Bull Exp Biol Med
; 156(4): 448-51, 2014 Feb.
Article
in En
| MEDLINE
| ID: mdl-24771424
ABSTRACT
We studied ultrastructure of synaptic connections between long-living dentate fascia transplants and somatosensory area of the neocortex in rats. Giant synaptic terminals of granular neurons upon contact with unusual neuronal targets in the neocortex reproduced their specific constitutive morphological features. At the same time, developing synapses with signs of active structural and metabolic reorganization were revealed. This is indicative of a dynamic state and instability of functional connections between the transplant and brain despite long time after transplantation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain Tissue Transplantation
/
Dentate Gyrus
Type of study:
Diagnostic_studies
Limits:
Animals
Language:
En
Journal:
Bull Exp Biol Med
Year:
2014
Document type:
Article