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Nanomicellar formulation of coenzyme Q10 (Ubisol-Q10) effectively blocks ongoing neurodegeneration in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model: potential use as an adjuvant treatment in Parkinson's disease.
Sikorska, Marianna; Lanthier, Patricia; Miller, Harvey; Beyers, Melissa; Sodja, Caroline; Zurakowski, Bogdan; Gangaraju, Sandhya; Pandey, Siyaram; Sandhu, Jagdeep K.
Affiliation
  • Sikorska M; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Lanthier P; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Miller H; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Beyers M; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Sodja C; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Zurakowski B; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Gangaraju S; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada.
  • Pandey S; Department of Chemistry and Biochemistry, University of Windsor Essex Hall, Windsor, Ontario, Canada.
  • Sandhu JK; Department of Translational Bioscience, Human Health Therapeutics Portfolio, National Research Council Canada, Ottawa, Ontario, Canada. Electronic address: jagdeep.sandhu@nrc.ca.
Neurobiol Aging ; 35(10): 2329-46, 2014 Oct.
Article in En | MEDLINE | ID: mdl-24775711
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Ubiquinone / Neuroprotective Agents / Nanoparticles / Micelles / Antioxidants Limits: Animals Language: En Journal: Neurobiol Aging Year: 2014 Document type: Article Affiliation country: Canada
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Ubiquinone / Neuroprotective Agents / Nanoparticles / Micelles / Antioxidants Limits: Animals Language: En Journal: Neurobiol Aging Year: 2014 Document type: Article Affiliation country: Canada