Immunohistochemical analysis of tau phosphorylation and astroglial activation with enhanced leptin receptor expression in diet-induced obesity mouse hippocampus.

Koga, Shunsuke; Kojima, Ayako; Kuwabara, Satoshi; Yoshiyama, Yasumasa

Koga, Shunsuke; Kojima, Ayako; Kuwabara, Satoshi; Yoshiyama, Yasumasa.

Affiliation

Koga S; Department of Neurology, Chiba University Graduate School of Medicine, Japan.
Kojima A; Laboratory for Neurodegenerative Disorder Research, Clinical Research Center, Chiba East National Hospital, Japan.
Kuwabara S; Department of Neurology, Chiba University Graduate School of Medicine, Japan.
Yoshiyama Y; Laboratory for Neurodegenerative Disorder Research, Clinical Research Center, Chiba East National Hospital, Japan; Department of Neurology, Chiba-East National Hospital, Japan; Department of Neurology, Chiba University Graduate School of Medicine, Japan. Electronic address: neuroyy@cehpnet.com.

Neurosci Lett ; 571: 11-6, 2014 Jun 13.

Article in En | MEDLINE | ID: mdl-24785100

Subject(s)

Astrocytes/pathology; Hippocampus/metabolism; Obesity/metabolism; Receptors, Leptin/metabolism; tau Proteins/metabolism; Animals; Dietary Fats; Female; Gliosis; Mice; Obesity/etiology; Obesity/pathology; Phosphorylation; Physical Conditioning, Animal; Weight Gain

Key words

Alzheimer disease; Astrocyte; Diet-induced obesity; Tau phosphorylation; Voluntary exercise; Wild-type mouse

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytes / Tau Proteins / Receptors, Leptin / Hippocampus / Obesity Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Neurosci Lett Year: 2014 Document type: Article Affiliation country: Japan Country of publication: Ireland

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