PEG-polypeptide block copolymers as pH-responsive endosome-solubilizing drug nanocarriers.

Quadir, Mohiuddin A; Morton, Stephen W; Deng, Zhou J; Shopsowitz, Kevin E; Murphy, Ryan P; Epps, Thomas H; Hammond, Paula T

Quadir, Mohiuddin A; Morton, Stephen W; Deng, Zhou J; Shopsowitz, Kevin E; Murphy, Ryan P; Epps, Thomas H; Hammond, Paula T.

Affiliation

Quadir MA; Department of Chemical Engineering and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.

Mol Pharm ; 11(7): 2420-30, 2014 Jul 07.

Article in En | MEDLINE | ID: mdl-24813025

Subject(s)

Drug Carriers/chemistry; Endosomes/chemistry; Nanoparticles/chemistry; Peptides/chemistry; Polyethylene Glycols/chemistry; Polymers/chemistry; Animals; Cell Line, Tumor; Doxorubicin/chemistry; Drug Delivery Systems/methods; Humans; Hydrogen-Ion Concentration; Mice; Mice, Inbred BALB C; Polymerization; Solubility

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Polyethylene Glycols / Polymers / Endosomes / Drug Carriers / Nanoparticles Limits: Animals / Humans Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States

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