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IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L.
Kryczek, Ilona; Lin, Yanwei; Nagarsheth, Nisha; Peng, Dongjun; Zhao, Lili; Zhao, Ende; Vatan, Linda; Szeliga, Wojciech; Dou, Yali; Owens, Scott; Zgodzinski, Witold; Majewski, Marek; Wallner, Grzegorz; Fang, Jingyuan; Huang, Emina; Zou, Weiping.
Affiliation
  • Kryczek I; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Lin Y; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Nagarsheth N; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao-Tong University, Shanghai 200001, China.
  • Peng D; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Zhao L; Graduate Programs in Immunology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Zhao E; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Vatan L; Department of Biostatistics, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Szeliga W; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Dou Y; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Owens S; Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Zgodzinski W; Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Majewski M; Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA.
  • Wallner G; The Second Department of General Surgery, Medical University in Lublin, Lublin 20-081, Poland.
  • Fang J; The Second Department of General Surgery, Medical University in Lublin, Lublin 20-081, Poland.
  • Huang E; The Second Department of General Surgery, Medical University in Lublin, Lublin 20-081, Poland.
  • Zou W; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao-Tong University, Shanghai 200001, China.
Immunity ; 40(5): 772-784, 2014 May 15.
Article in En | MEDLINE | ID: mdl-24816405
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Colorectal Neoplasms / CD4-Positive T-Lymphocytes / Interleukins / STAT3 Transcription Factor / Methyltransferases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Colorectal Neoplasms / CD4-Positive T-Lymphocytes / Interleukins / STAT3 Transcription Factor / Methyltransferases Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States