Mutation frequency dynamics in HPRT locus in culture-adapted human embryonic stem cells and induced pluripotent stem cells correspond to their differentiated counterparts.

Krutá, Miriama; Seneklová, Monika; Raska, Jan; Salykin, Anton; Zerzánková, Lenka; Pesl, Martin; Bártová, Eva; Franek, Michal; Baumeisterová, Aneta; Kosková, Stanislava; Neelsen, Kai J; Hampl, Ales; Dvorák, Petr; Rotrekl, Vladimír

Krutá, Miriama; Seneklová, Monika; Raska, Jan; Salykin, Anton; Zerzánková, Lenka; Pesl, Martin; Bártová, Eva; Franek, Michal; Baumeisterová, Aneta; Kosková, Stanislava; Neelsen, Kai J; Hampl, Ales; Dvorák, Petr; Rotrekl, Vladimír.

Affiliation

Krutá M; 1 Department of Biology, Faculty of Medicine, Masaryk University , Brno, Czech Republic .

Stem Cells Dev ; 23(20): 2443-54, 2014 Oct 15.

Article in En | MEDLINE | ID: mdl-24836366

Subject(s)

Genetic Loci; Hypoxanthine Phosphoribosyltransferase/genetics; Induced Pluripotent Stem Cells/metabolism; Mutation Rate; Cell Differentiation/radiation effects; Cell Line; Gamma Rays; Humans; Hypoxanthine Phosphoribosyltransferase/metabolism; Induced Pluripotent Stem Cells/cytology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Induced Pluripotent Stem Cells / Genetic Loci / Mutation Rate / Hypoxanthine Phosphoribosyltransferase Limits: Humans Language: En Journal: Stem Cells Dev Journal subject: HEMATOLOGIA Year: 2014 Document type: Article Affiliation country: Czech Republic

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