Hyperbaric oxygen for the treatment of nonhealing arterial insufficiency ulcers.
Wound Repair Regen
; 22(3): 351-5, 2014.
Article
in En
| MEDLINE
| ID: mdl-24844334
ABSTRACT
There is limited data regarding hyperbaric oxygen's effectiveness in the treatment of nonhealing arterial insufficiency ulcers. This study was designed to analyze healing rates and amputation rates in patients who underwent adjunctive hyperbaric oxygen for a nonhealing arterial insufficiency ulcer. A retrospective chart review was completed on patients who underwent hyperbaric oxygen for arterial insufficiency ulcers that failed to heal despite standard treatment. Information collected included complete ulcer healing, amputation, and patient characteristics. There were 82 patients identified. A majority did not have diabetes (84.1%). The overall rate of healing was 43.9%. The overall major amputation rate was 17.1%. The amputation rate among those who healed was 0% compared to 42.4% among those not healed (p < 0.0001). Dialysis was predictive of major amputation (p = 0.03). Our findings suggest hyperbaric oxygen can play a role in management of arterial insufficiency ulcers that have failed standard treatment. The overwhelming majority of these patients did not have diabetes, which allows this study to be translated to patients with a primary arterial insufficiency ulcer. These results support the use of hyperbaric oxygen for select nonhealing arterial insufficiency ulcers that have failed standard therapy and the need for a prospective pilot study.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Varicose Ulcer
/
Wound Healing
/
Limb Salvage
/
Pressure Ulcer
/
Hyperbaric Oxygenation
/
Leg Ulcer
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
En
Journal:
Wound Repair Regen
Journal subject:
DERMATOLOGIA
Year:
2014
Document type:
Article