Cimetidine attenuates vinorelbine-induced phlebitis in mice by militating E-selectin expression.

Wang, Zhuo; Ma, Lijuan; Wang, Xuebin; Cai, Heping; Huang, Jin; Liu, Jiyong; Hu, Jinhong; Su, Dingfeng

Wang, Zhuo; Ma, Lijuan; Wang, Xuebin; Cai, Heping; Huang, Jin; Liu, Jiyong; Hu, Jinhong; Su, Dingfeng.

Affiliation

Wang Z; Department of Pharmacy, Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.

Cancer Chemother Pharmacol ; 74(2): 239-47, 2014 Aug.

Article in En | MEDLINE | ID: mdl-24879290

Subject(s)

Antineoplastic Agents, Phytogenic/toxicity; Cimetidine/therapeutic use; E-Selectin/physiology; Histamine H2 Antagonists/therapeutic use; Phlebitis/drug therapy; Vinblastine/analogs & derivatives; Animals; Blotting, Western; Cell Proliferation/drug effects; Cells, Cultured; Endothelium, Vascular/cytology; Endothelium, Vascular/drug effects; Endothelium, Vascular/metabolism; Flow Cytometry; Humans; Infusions, Intravenous; Mice; Mice, Inbred C57BL; Mice, Knockout; Phlebitis/chemically induced; Phlebitis/metabolism; RNA, Messenger/genetics; Rabbits; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Vinblastine/toxicity; Vinorelbine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phlebitis / Vinblastine / Cimetidine / E-Selectin / Histamine H2 Antagonists / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Chemother Pharmacol Year: 2014 Document type: Article Affiliation country: China Country of publication: Germany

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