Differential impact on acute kidney injury incidence between on- and off pump coronary artery bypass grafting in octogenarians.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
; 159(3): 449-54, 2015 Sep.
Article
in En
| MEDLINE
| ID: mdl-24881588
ABSTRACT
INTRODUCTION:
Acute kidney injury (AKI) following surgical myocardial revascularization is associated with high mortality and morbidity. The aim of this study was to evaluate the risk of acute kidney injury in a population of very old patients following different surgical techniques. PATIENTS ANDMETHODS:
A retrospective study of 310 consecutive patients aged 78 to 93 years, mean 80.5±2.2, who underwent surgery at one cardiac surgery centre. Based on the surgical technique used the patients were divided into Group I. CABG (n=134) - surgical myocardial revascularization using extracorporeal circulation and arterial and venous grafts. Group II. OPCABG (n=55) - surgical revascularization without extracorporeal circulation but using arterial and venous grafts. Group III. NOTOUCH (n=121) - no handling with the ascending aorta was performed at all.RESULTS:
A statistically insignificant renoprotective trend was found in patients who underwent surgery without extracorporeal circulation regardless of technique. Comparing groups II and III vs. group I, a significantly poorer renal functioning (median difference in creatinine was 10.0 (32.9) vs 17.5 (35.0), P=0.05) was shown for patients in group I.CONCLUSION:
Surgical myocardial revascularization without extracorporeal circulation in very old patients is safe. The results of this study show a renoprotective trend.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Postoperative Complications
/
Coronary Artery Disease
/
Risk Assessment
/
Acute Kidney Injury
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
En
Journal:
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
Journal subject:
MEDICINA
Year:
2015
Document type:
Article
Affiliation country:
Czech Republic