Specific antioxidant compounds differentially modulate cytotoxic activity of doxorubicin and cisplatin: in vitro and in vivo study.

Panchuk, Rostyslav; Skorokhyd, Nadia; Chumak, Vira; Lehka, Lilya; Omelyanchik, Sofya; Gurinovich, Valery; Moiseenok, Andrey; Heffeter, Petra; Berger, Walter; Stoika, Rostyslav

Panchuk, Rostyslav; Skorokhyd, Nadia; Chumak, Vira; Lehka, Lilya; Omelyanchik, Sofya; Gurinovich, Valery; Moiseenok, Andrey; Heffeter, Petra; Berger, Walter; Stoika, Rostyslav.

Affiliation

Panchuk R; Rostyslav Panchuk, Institute of Cell Biology, National Academy of Sciences of Ukraine, Drahomanov Street 14/16, 79005, Lviv, Ukraine, rpanchuk@ukr.net.

Croat Med J ; 55(3): 206-17, 2014 Jun 01.

Article in En | MEDLINE | ID: mdl-24891279

Subject(s)

Antineoplastic Agents/toxicity; Antioxidants/pharmacology; Cisplatin/toxicity; Doxorubicin/toxicity; Pantetheine/analogs & derivatives; Selenomethionine/pharmacology; Sodium Selenite/pharmacology; Animals; Apoptosis/drug effects; Drug Synergism; HCT116 Cells; HL-60 Cells; Humans; Jurkat Cells; Male; Oxidation-Reduction; Oxidoreductases/metabolism; Pantetheine/pharmacology; Rats; Rats, Wistar; Tumor Cells, Cultured/drug effects; Tumor Cells, Cultured/enzymology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pantetheine / Selenomethionine / Doxorubicin / Cisplatin / Sodium Selenite / Antineoplastic Agents / Antioxidants Limits: Animals / Humans / Male Language: En Journal: Croat Med J Journal subject: MEDICINA Year: 2014 Document type: Article Country of publication: Croatia

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