Host STAT2/type I interferon axis controls tumor growth.

Yue, Chanyu; Xu, Jun; Tan Estioko, Marc Daryl; Kotredes, Kevin P; Lopez-Otalora, Yolanda; Hilliard, Brendan A; Baker, Darren P; Gallucci, Stefania; Gamero, Ana M

Yue, Chanyu; Xu, Jun; Tan Estioko, Marc Daryl; Kotredes, Kevin P; Lopez-Otalora, Yolanda; Hilliard, Brendan A; Baker, Darren P; Gallucci, Stefania; Gamero, Ana M.

Affiliation

Yue C; Department of Biochemistry, Temple University School of Medicine, Philadelphia, PA.

Int J Cancer ; 136(1): 117-26, 2015 Jan 01.

Article in En | MEDLINE | ID: mdl-24895110

Subject(s)

Antineoplastic Agents/pharmacology; Interferon-beta/pharmacology; Lung Neoplasms/secondary; Melanoma, Experimental/pathology; STAT2 Transcription Factor/physiology; Tumor Burden/immunology; Adoptive Transfer; Animals; Cell Line, Tumor; Culture Media, Conditioned; Dendritic Cells; Down-Regulation; Gene Expression Regulation, Neoplastic/immunology; Lung Neoplasms/immunology; Lung Neoplasms/therapy; Melanoma, Experimental/immunology; Melanoma, Experimental/therapy; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasm Transplantation; STAT1 Transcription Factor/metabolism; T-Lymphocytes/immunology

Key words

STAT1; STAT2; antitumor; cross-presentation; dendritic cell; interferon; melanoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Melanoma, Experimental / Interferon-beta / Tumor Burden / STAT2 Transcription Factor / Lung Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Int J Cancer Year: 2015 Document type: Article Affiliation country: Panama Country of publication: United States

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