In vitro antileukaemic activity of extracts from Daphne gnidium leaves against sensitive and multidrug resistant K562/R7 cells.

Chaabane, Fadwa; Krifa, Mounira; Matera, Eva; Loussaeif, Amira; Dijoux-Franca, Marie-Geneviève; Ghedira, Kamel; Dumontet, Charles; Chekir-Ghedira, Leila

Chaabane, Fadwa; Krifa, Mounira; Matera, Eva; Loussaeif, Amira; Dijoux-Franca, Marie-Geneviève; Ghedira, Kamel; Dumontet, Charles; Chekir-Ghedira, Leila.

Affiliation

Chaabane F; Unité de Substances Naturelles Bioactives et Biotechnologie UR12ES12, Faculté de Pharmacie de Monastir, Université de Monastir, Monastir, Tunisie.

Tumour Biol ; 35(9): 8991-8, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24903378

Subject(s)

Antineoplastic Agents/pharmacology; Cell Proliferation/drug effects; Daphne/chemistry; Plant Leaves/chemistry; ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors; ATP Binding Cassette Transporter, Subfamily B/metabolism; Acetates/chemistry; Butanols/chemistry; Cell Cycle Checkpoints/drug effects; Cell Survival/drug effects; Dose-Response Relationship, Drug; Drug Resistance, Multiple/drug effects; Flavonoids/analysis; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Leukemia, Erythroblastic, Acute/metabolism; Leukemia, Erythroblastic, Acute/pathology; Plant Extracts/chemistry; Plant Extracts/pharmacology; Polyphenols/analysis; Solvents/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Leaves / Daphne / Cell Proliferation / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Tumour Biol Journal subject: NEOPLASIAS Year: 2014 Document type: Article Affiliation country: Tunisia Country of publication: Netherlands

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