The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization.

Fousteri, G; Jofra, T; Debernardis, I; Stanford, S M; Laurenzi, A; Bottini, N; Battaglia, M

Fousteri, G; Jofra, T; Debernardis, I; Stanford, S M; Laurenzi, A; Bottini, N; Battaglia, M.

Affiliation

Fousteri G; Diabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy.

Clin Exp Immunol ; 178(1): 178-89, 2014 Oct.

Article in En | MEDLINE | ID: mdl-24905474

Subject(s)

Forkhead Transcription Factors/immunology; Protein Tyrosine Phosphatase, Non-Receptor Type 22/immunology; T-Lymphocytes, Regulatory/immunology; Th1 Cells/immunology; Animals; CD4-Positive T-Lymphocytes/immunology; Cell Differentiation/immunology; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Antigen, T-Cell/immunology

Key words

FoxP3+ Treg cells; PTPN22; Th1 cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Th1 Cells / Forkhead Transcription Factors / Protein Tyrosine Phosphatase, Non-Receptor Type 22 Limits: Animals / Humans Language: En Journal: Clin Exp Immunol Year: 2014 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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