Neuronal deletion of GSK3ß increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.

Liz, Márcia A; Mar, Fernando M; Santos, Telma E; Pimentel, Helena I; Marques, Ana M; Morgado, Marlene M; Vieira, Sílvia; Sousa, Vera F; Pemble, Hayley; Wittmann, Torsten; Sutherland, Calum; Woodgett, James R; Sousa, Mónica M

Liz, Márcia A; Mar, Fernando M; Santos, Telma E; Pimentel, Helena I; Marques, Ana M; Morgado, Marlene M; Vieira, Sílvia; Sousa, Vera F; Pemble, Hayley; Wittmann, Torsten; Sutherland, Calum; Woodgett, James R; Sousa, Mónica M.

BMC Biol ; 12: 47, 2014 Jun 12.

Article in En | MEDLINE | ID: mdl-24923837

Subject(s)

Axons/physiology; Glycogen Synthase Kinase 3/genetics; Growth Cones/metabolism; Microtubules/metabolism; Regeneration; Animals; Female; Glycogen Synthase Kinase 3/metabolism; Glycogen Synthase Kinase 3 beta; Intercellular Signaling Peptides and Proteins/genetics; Intercellular Signaling Peptides and Proteins/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins/genetics; Microtubule-Associated Proteins/metabolism; Nerve Tissue Proteins/genetics; Nerve Tissue Proteins/metabolism; Phosphorylation; Rats; Rats, Wistar

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regeneration / Axons / Growth Cones / Glycogen Synthase Kinase 3 / Microtubules Type of study: Prognostic_studies Limits: Animals Language: En Journal: BMC Biol Journal subject: BIOLOGIA Year: 2014 Document type: Article Country of publication: United kingdom

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