Adipose tissue changes in obesity and the impact on metabolic function.
Transl Res
; 164(4): 284-92, 2014 Oct.
Article
in En
| MEDLINE
| ID: mdl-24929206
ABSTRACT
Obesity is associated with adverse alterations in adipose tissue that predispose to metabolic dysregulation. These adverse alterations include accumulation of inflammatory macrophages leading to the activation of inflammation pathways, reduction in lipid turnover, and deposition of fat in ectopic locations. These alterations are precursors to the development of insulin resistance and metabolic dysfunction.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adipose Tissue
/
Energy Metabolism
/
Obesity
Limits:
Humans
Language:
En
Journal:
Transl Res
Journal subject:
MEDICINA
/
TECNICAS E PROCEDIMENTOS DE LABORATORIO
Year:
2014
Document type:
Article