Implant debris particle size affects serum protein adsorption which may contribute to particle size-based bioreactivity differences.

Reddy, Anand; Caicedo, Marco S; Samelko, Lauryn; Jacobs, Joshua J; Hallab, Nadim James

Reddy, Anand; Caicedo, Marco S; Samelko, Lauryn; Jacobs, Joshua J; Hallab, Nadim James.

Affiliation

Reddy A; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Caicedo MS; Orthopedic Analysis, LLC, Chicago, IL 60612; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Samelko L; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Jacobs JJ; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.
Hallab NJ; Orthopedic Analysis, LLC, Department of Immunology, Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.

J Long Term Eff Med Implants ; 24(1): 77-88, 2014.

Article in En | MEDLINE | ID: mdl-24941408

Subject(s)

Adsorption; Fibronectins/metabolism; Immunoglobulin G/metabolism; Particle Size; Serum Albumin/metabolism; Adult; Cell Survival; Cells, Cultured; Chromium Alloys; Female; Fibronectins/pharmacology; Healthy Volunteers; Humans; Immunoglobulin G/pharmacology; Interleukin-1beta/metabolism; Macrophages/drug effects; Macrophages/metabolism; Male; Middle Aged; Molecular Weight; Monocytes/drug effects; Monocytes/metabolism; Serum Albumin/pharmacology; Tumor Necrosis Factor-alpha/metabolism; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Particle Size / Immunoglobulin G / Serum Albumin / Fibronectins / Adsorption Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Long Term Eff Med Implants Year: 2014 Document type: Article Country of publication: United States

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