Crosstalk between DNA repair and cancer stem cell (CSC) associated intracellular pathways.

Skvortsov, Sergej; Debbage, Paul; Lukas, Peter; Skvortsova, Ira

Skvortsov, Sergej; Debbage, Paul; Lukas, Peter; Skvortsova, Ira.

Affiliation

Skvortsov S; Department of Therapeutic Radiology and Oncology, Innsbruck Medical University, Innsbruck, Austria. Electronic address: Sergej.Skvortsov@i-med.ac.at.
Debbage P; Department of Anatomy, Histology and Embryology, Innsbruck Medical University, Innsbruck, Austria.
Lukas P; Department of Therapeutic Radiology and Oncology, Innsbruck Medical University, Innsbruck, Austria.
Skvortsova I; Department of Therapeutic Radiology and Oncology, Innsbruck Medical University, Innsbruck, Austria.

Semin Cancer Biol ; 31: 36-42, 2015 Apr.

Article in En | MEDLINE | ID: mdl-24954010

Subject(s)

DNA Damage; DNA Repair; Neoplasms/genetics; Neoplastic Stem Cells/metabolism; Signal Transduction/genetics; Antineoplastic Agents/therapeutic use; DNA-(Apurinic or Apyrimidinic Site) Lyase/genetics; DNA-(Apurinic or Apyrimidinic Site) Lyase/metabolism; Gene Expression Regulation, Neoplastic/drug effects; Humans; Models, Genetic; Neoplasms/drug therapy; Neoplasms/metabolism; Neoplastic Stem Cells/drug effects; Neoplastic Stem Cells/pathology; Signal Transduction/drug effects

Key words

Ape1/Ref-1; Cancer stem cells; DNA repair; Intracellular signalling; MRN complex

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / DNA Damage / Signal Transduction / DNA Repair / Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Semin Cancer Biol Journal subject: NEOPLASIAS Year: 2015 Document type: Article Country of publication: United kingdom

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