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Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth.
Shan, Changliang; Kang, Hee-Bum; Elf, Shannon; Xie, Jianxin; Gu, Ting-Lei; Aguiar, Mike; Lonning, Scott; Hitosugi, Taro; Chung, Tae-Wook; Arellano, Martha; Khoury, Hanna J; Shin, Dong M; Khuri, Fadlo R; Boggon, Titus J; Fan, Jun.
Affiliation
  • Shan C; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Kang HB; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Elf S; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Xie J; Cell Signaling Technology, Inc., Danvers, Massachusetts 01923, and.
  • Gu TL; Cell Signaling Technology, Inc., Danvers, Massachusetts 01923, and.
  • Aguiar M; Cell Signaling Technology, Inc., Danvers, Massachusetts 01923, and.
  • Lonning S; Cell Signaling Technology, Inc., Danvers, Massachusetts 01923, and.
  • Hitosugi T; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Chung TW; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Arellano M; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Khoury HJ; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Shin DM; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Khuri FR; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322.
  • Boggon TJ; the Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520.
  • Fan J; From the Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, Georgia 30322, jfan3@emory.edu.
J Biol Chem ; 289(31): 21413-22, 2014 Aug 01.
Article in En | MEDLINE | ID: mdl-24962578
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Cell Division / Pyruvate Dehydrogenase (Lipoamide)-Phosphatase / Neoplasms Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2014 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Cell Division / Pyruvate Dehydrogenase (Lipoamide)-Phosphatase / Neoplasms Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2014 Document type: Article Country of publication: United States