In vitro/in vivo screening of oxidative homeostasis and damage to DNA, protein, and lipids using UPLC/MS-MS.

Carretero, Aitor; León, Zacarías; García-Cañaveras, Juan Carlos; Zaragoza, Angela; Gómez-Lechón, María José; Donato, María Teresa; Lahoz, Agustín

Carretero, Aitor; León, Zacarías; García-Cañaveras, Juan Carlos; Zaragoza, Angela; Gómez-Lechón, María José; Donato, María Teresa; Lahoz, Agustín.

Affiliation

Carretero A; Unidad de Hepatología Experimental, Instituto de Investigación Sanitaria - Fundación Hospital La Fe, CIBERehd, Centro de Investigaciones Biomédicas en Red de Enfermedades Hepáticas y Digestivas, FIS, 46026, Valencia, Spain.

Anal Bioanal Chem ; 406(22): 5465-76, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24969468

Subject(s)

DNA Damage; Lipids/chemistry; Liver/metabolism; Oxygen/chemistry; Proteins/chemistry; Animals; Biomarkers/metabolism; Chromatography, High Pressure Liquid; Glutathione Transferase/analysis; Hepatocytes/metabolism; Homeostasis; Humans; Male; Malondialdehyde/analysis; Non-alcoholic Fatty Liver Disease/diagnosis; Non-alcoholic Fatty Liver Disease/metabolism; Oxidative Stress; Perfusion; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / DNA Damage / Proteins / Lipids / Liver Type of study: Diagnostic_studies / Guideline / Prognostic_studies / Screening_studies Limits: Animals / Humans / Male Language: En Journal: Anal Bioanal Chem Year: 2014 Document type: Article Affiliation country: Spain Country of publication: Germany

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