Vagus nerve stimulator implantation for epilepsy in a paediatric hospital: outcomes and effect on quality of life.
Neurologia
; 30(8): 465-71, 2015 Oct.
Article
in En, Es
| MEDLINE
| ID: mdl-24975345
ABSTRACT
INTRODUCTION:
Epilepsy, which is present in 0.5% to 1% of the paediatric population, is one of the most frequent childhood neurological disorders. Approximately 20% to 30% of these cases will be drug-resistant. The objective of this study is to describe the impact of vagal nerve stimulation (VNS) on seizures and quality of life in a sample of 30 patients.METHODS:
Descriptive, retrospective study of all patients with a VNS device implanted between 2008 and 2013 in a single paediatric hospital, based on patients' medical records. Quality of life was assessed using the Spanish scale for quality of life in children with epilepsy, completed by means of a telephone interview.RESULTS:
We describe a population of 19 boys (64%) and 11 girls (36%) with a mean age at seizure onset of 21 months (1-144 months). The mean age of VNS implantation was 11.89 years. Follow-up periods ranged from 6 to 36 months. Mean reduction in seizures at 6 months was 38%, with a reduction of 43% at 12 months, 42% at 24 months, and 54% at 36 months. At least half of all patients were classified as responders. According to the quality of life scale, 54% of the families rated the effect of VNS as either very good or good while 39% rated it as fair.CONCLUSIONS:
VNS is a safe palliative treatment that is generally well tolerated. It is partially effective for controlling drug-resistant epilepsy and exerts a positive effect on quality of life.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quality of Life
/
Vagus Nerve Stimulation
/
Drug Resistant Epilepsy
Type of study:
Etiology_studies
/
Observational_studies
Aspects:
Patient_preference
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
En
/
Es
Journal:
Neurologia
Journal subject:
NEUROLOGIA
Year:
2015
Document type:
Article