BMP-7 attenuates adverse cardiac remodeling mediated through M2 macrophages in prediabetic cardiomyopathy.

Urbina, Princess; Singla, Dinender K

Urbina, Princess; Singla, Dinender K.

Affiliation

Urbina P; Biomolecular Science Center, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida.
Singla DK; Biomolecular Science Center, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida Dinender.Singla@ucf.edu.

Am J Physiol Heart Circ Physiol ; 307(5): H762-72, 2014 Sep 01.

Article in En | MEDLINE | ID: mdl-24993041

Subject(s)

Bone Morphogenetic Protein 7/pharmacology; Diabetic Cardiomyopathies/drug therapy; Monocyte-Macrophage Precursor Cells/drug effects; Ventricular Remodeling/drug effects; Animals; Apoptosis; Bone Morphogenetic Protein 7/therapeutic use; Cell Differentiation; Cell Movement; Diabetic Cardiomyopathies/pathology; Fibrosis/drug therapy; Mice; Mice, Inbred C57BL; Monocyte-Macrophage Precursor Cells/cytology; Monocyte-Macrophage Precursor Cells/physiology

Key words

apoptosis; bone morphogenetic protein-7; heart; macrophages; monocytes; prediabetic cardiomyopathy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ventricular Remodeling / Monocyte-Macrophage Precursor Cells / Bone Morphogenetic Protein 7 / Diabetic Cardiomyopathies Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2014 Document type: Article Country of publication: United States

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