Lactobacillus delbrueckii TUA4408L and its extracellular polysaccharides attenuate enterotoxigenic Escherichia coli-induced inflammatory response in porcine intestinal epitheliocytes via Toll-like receptor-2 and 4.

Wachi, Satoshi; Kanmani, Paulraj; Tomosada, Yohsuke; Kobayashi, Hisakazu; Yuri, Toshihito; Egusa, Shintaro; Shimazu, Tomoyuki; Suda, Yoshihito; Aso, Hisashi; Sugawara, Makoto; Saito, Tadao; Mishima, Takashi; Villena, Julio; Kitazawa, Haruki

Wachi, Satoshi; Kanmani, Paulraj; Tomosada, Yohsuke; Kobayashi, Hisakazu; Yuri, Toshihito; Egusa, Shintaro; Shimazu, Tomoyuki; Suda, Yoshihito; Aso, Hisashi; Sugawara, Makoto; Saito, Tadao; Mishima, Takashi; Villena, Julio; Kitazawa, Haruki.

Affiliation

Wachi S; Food and Feed Immunology Group, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.

Mol Nutr Food Res ; 58(10): 2080-93, 2014 Oct.

Article in En | MEDLINE | ID: mdl-24995380

Subject(s)

Enterocytes/immunology; Enterotoxigenic Escherichia coli/immunology; Immunity, Mucosal; Lactobacillus delbrueckii/immunology; Polysaccharides, Bacterial/pharmacology; Toll-Like Receptor 2/agonists; Toll-Like Receptor 4/agonists; Animals; Calcium Signaling/drug effects; Cell Line; Cytokines/agonists; Cytokines/metabolism; Enterocytes/metabolism; Enterocytes/microbiology; Immunity, Mucosal/drug effects; Lactobacillus delbrueckii/metabolism; MAP Kinase Signaling System/drug effects; Polysaccharides, Bacterial/metabolism; Probiotics/metabolism; RNA Interference; RNA, Small Interfering; Surface Properties; Sus scrofa; Toll-Like Receptor 2/antagonists & inhibitors; Toll-Like Receptor 2/genetics; Toll-Like Receptor 2/metabolism; Toll-Like Receptor 4/antagonists & inhibitors; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism

Key words

Anti-inflammatory activity; Extracellular polysaccharides; L. delbrueckii; PIE cells; TLR negative regulators; TLR2; TLR4

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Immunity, Mucosal / Enterocytes / Lactobacillus delbrueckii / Toll-Like Receptor 2 / Toll-Like Receptor 4 / Enterotoxigenic Escherichia coli Limits: Animals Language: En Journal: Mol Nutr Food Res Journal subject: CIENCIAS DA NUTRICAO Year: 2014 Document type: Article Affiliation country: Japan Country of publication: Germany

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