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Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs.
Smith, Cory; Gore, Athurva; Yan, Wei; Abalde-Atristain, Leire; Li, Zhe; He, Chaoxia; Wang, Ying; Brodsky, Robert A; Zhang, Kun; Cheng, Linzhao; Ye, Zhaohui.
Affiliation
  • Smith C; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Predoctoral Training Program in Human Genetics, Johns Hopki
  • Gore A; Department of Bioengineering, Institute for Genomic Medicine and Institute of Engineering in Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
  • Yan W; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Abalde-Atristain L; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Cellular and Molecular Medicine Graduate Program, Johns Hop
  • Li Z; Department of Bioengineering, Institute for Genomic Medicine and Institute of Engineering in Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
  • He C; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Wang Y; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Chemical and Biomolecular Engineering, Johns
  • Brodsky RA; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Zhang K; Department of Bioengineering, Institute for Genomic Medicine and Institute of Engineering in Medicine, University of California at San Diego, La Jolla, CA 92093, USA.
  • Cheng L; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Predoctoral Training Program in Human Genetics, Johns Hopki
  • Ye Z; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Stem Cell Program, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: zye@jhmi.edu.
Cell Stem Cell ; 15(1): 12-3, 2014 Jul 03.
Article in En | MEDLINE | ID: mdl-24996165
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Sequence Analysis, DNA / Endonucleases / Induced Pluripotent Stem Cells / CRISPR-Cas Systems Limits: Humans Language: En Journal: Cell Stem Cell Year: 2014 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Sequence Analysis, DNA / Endonucleases / Induced Pluripotent Stem Cells / CRISPR-Cas Systems Limits: Humans Language: En Journal: Cell Stem Cell Year: 2014 Document type: Article Country of publication: United States