Comparison of immunogenicity of combined DPT--inactivated injectable polio vaccine (DPT - IPV) and association of DPT and attenuated oral polio vaccine (DPT + OPV) in Pakistani children.
J Pak Med Assoc
; 39(2): 31-5, 1989 Feb.
Article
in En
| MEDLINE
| ID: mdl-2499700
ABSTRACT
Two hundred children aged 2-24 months attending EPI Centre Rawalpindi General Hospital, were randomly assigned to two basic immunization schedules i.e. 3 doses of oral polio vaccine alongwith two doses of DPT (Conventional Schedule) and 2 doses of combined DPT - enhanced injectable polio vaccine (new simplified schedule). Comparison of the seroconversion results showed the presence of protective antibodies against all the 3 types of polio in 100% of the children in both the groups, but there was no statistical difference in the geometric mean antibody titre in the two immunization schedules. After two doses of DPT-IPV or DPT vaccine alone the results demonstrated antibody levels above the protective threshold in both the groups against Diphtheria, Pertussis and Tetanus.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Diphtheria Toxoid
/
Tetanus Toxoid
/
Pertussis Vaccine
/
Poliovirus Vaccine, Inactivated
/
Poliovirus Vaccine, Oral
/
Antibody Formation
Type of study:
Clinical_trials
/
Risk_factors_studies
Limits:
Child, preschool
/
Humans
/
Infant
Country/Region as subject:
Asia
Language:
En
Journal:
J Pak Med Assoc
Year:
1989
Document type:
Article