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Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo.
Polykratis, Apostolos; Hermance, Nicole; Zelic, Matija; Roderick, Justine; Kim, Chun; Van, Trieu-My; Lee, Thomas H; Chan, Francis K M; Pasparakis, Manolis; Kelliher, Michelle A.
Affiliation
  • Polykratis A; Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50674 Cologne, Germany.
  • Hermance N; Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Zelic M; Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Roderick J; Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Kim C; Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50674 Cologne, Germany.
  • Van TM; Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50674 Cologne, Germany.
  • Lee TH; Genentech, San Francisco, CA.
  • Chan FKM; Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Pasparakis M; Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50674 Cologne, Germany.
  • Kelliher MA; Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
J Immunol ; 193(4): 1539-1543, 2014 Aug 15.
Article in En | MEDLINE | ID: mdl-25015821
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Apoptosis / Receptor-Interacting Protein Serine-Threonine Kinases / Hypothermia / Necrosis Limits: Animals Language: En Journal: J Immunol Year: 2014 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Apoptosis / Receptor-Interacting Protein Serine-Threonine Kinases / Hypothermia / Necrosis Limits: Animals Language: En Journal: J Immunol Year: 2014 Document type: Article Affiliation country: Germany Country of publication: United States