Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules.

Salem, Omar; Wang, Hong Tian; Alaseem, Abdulrahman M; Ciobanu, Ovidiu; Hadjab, Insaf; Gawri, Rahul; Antoniou, John; Mwale, Fackson

Salem, Omar; Wang, Hong Tian; Alaseem, Abdulrahman M; Ciobanu, Ovidiu; Hadjab, Insaf; Gawri, Rahul; Antoniou, John; Mwale, Fackson.

Arthritis Res Ther ; 16(4): R152, 2014 Jul 17.

Article in En | MEDLINE | ID: mdl-25034046

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/adverse effects; Hedgehog Proteins/metabolism; Mesenchymal Stem Cells/drug effects; Naproxen/adverse effects; Osteogenesis/drug effects; Signal Transduction/drug effects; Cell Differentiation/drug effects; Gene Expression/drug effects; Humans; Mesenchymal Stem Cells/cytology; Mesenchymal Stem Cells/metabolism; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Signal Transduction / Anti-Inflammatory Agents, Non-Steroidal / Naproxen / Hedgehog Proteins / Mesenchymal Stem Cells Limits: Humans Language: En Journal: Arthritis Res Ther Journal subject: REUMATOLOGIA Year: 2014 Document type: Article Country of publication: United kingdom

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