Reduction of adhesion molecule production and alteration of eNOS and endothelin-1 mRNA expression in endothelium by Euphorbia hirta L. through its beneficial ß-amyrin molecule.

Shih, Mei Fen; Cherng, Jong Yuh

Shih, Mei Fen; Cherng, Jong Yuh.

Affiliation

Shih MF; Department of Pharmacy, Chia-Nan University of Pharmacy & Science, Tainan 717, Taiwan. meifenshih@mail.chna.edu.tw.
Cherng JY; Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi 621, Taiwan. jycherng@yahoo.com.

Molecules ; 19(7): 10534-45, 2014 Jul 18.

Article in En | MEDLINE | ID: mdl-25045892

Subject(s)

Endothelial Cells/metabolism; Endothelin-1/biosynthesis; Euphorbia/chemistry; Gene Expression Regulation/drug effects; Intercellular Adhesion Molecule-1/biosynthesis; Nitric Oxide Synthase Type III/biosynthesis; Oleanolic Acid/analogs & derivatives; RNA, Messenger/biosynthesis; Vascular Cell Adhesion Molecule-1/biosynthesis; Cell Line; Endothelial Cells/cytology; Humans; Oleanolic Acid/chemistry; Oleanolic Acid/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / RNA, Messenger / Gene Expression Regulation / Intercellular Adhesion Molecule-1 / Vascular Cell Adhesion Molecule-1 / Endothelin-1 / Euphorbia / Endothelial Cells / Nitric Oxide Synthase Type III Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2014 Document type: Article Affiliation country: Taiwan

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