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Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage.
Clewell, Rebecca A; Sun, Bin; Adeleye, Yeyejide; Carmichael, Paul; Efremenko, Alina; McMullen, Patrick D; Pendse, Salil; Trask, O J; White, Andy; Andersen, Melvin E.
Affiliation
  • Clewell RA; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 rclewell@thehamner.org.
  • Sun B; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
  • Adeleye Y; Unilever, Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK.
  • Carmichael P; Unilever, Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK.
  • Efremenko A; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
  • McMullen PD; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
  • Pendse S; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
  • Trask OJ; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
  • White A; Unilever, Safety and Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK.
  • Andersen ME; The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709.
Toxicol Sci ; 142(1): 56-73, 2014 Nov.
Article in En | MEDLINE | ID: mdl-25078064
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / DNA Damage / Signal Transduction / Tumor Suppressor Protein p53 / Micronuclei, Chromosome-Defective / Mutagens Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2014 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / DNA Damage / Signal Transduction / Tumor Suppressor Protein p53 / Micronuclei, Chromosome-Defective / Mutagens Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2014 Document type: Article Country of publication: United States