&#916;Np63&#945; enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2.

Ram Kumar, Ram Mohan; Betz, Michael M; Robl, Bernhard; Born, Walter; Fuchs, Bruno

ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2.

Ram Kumar, Ram Mohan; Betz, Michael M; Robl, Bernhard; Born, Walter; Fuchs, Bruno.

Affiliation

Ram Kumar RM; Laboratory for Orthopaedic Research, Department of Orthopaedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland. rkumar@research.balgrist.ch.

BMC Cancer ; 14: 559, 2014 Aug 01.

Article in En | MEDLINE | ID: mdl-25085524

Subject(s)

Kruppel-Like Transcription Factors/genetics; Nuclear Proteins/genetics; Osteosarcoma/pathology; Transcription Factors/genetics; Transcription Factors/metabolism; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Kruppel-Like Transcription Factors/metabolism; Nuclear Proteins/metabolism; Osteosarcoma/metabolism; Protein Isoforms/genetics; Protein Isoforms/metabolism; Signal Transduction; Tissue Array Analysis; Zinc Finger Protein Gli2

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Osteosarcoma / Tumor Suppressor Proteins / Kruppel-Like Transcription Factors Type of study: Prognostic_studies Limits: Humans Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2014 Document type: Article Affiliation country: Switzerland

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