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Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.
Cortes, Constanza J; Miranda, Helen C; Frankowski, Harald; Batlevi, Yakup; Young, Jessica E; Le, Amy; Ivanov, Nishi; Sopher, Bryce L; Carromeu, Cassiano; Muotri, Alysson R; Garden, Gwenn A; La Spada, Albert R.
Affiliation
  • Cortes CJ; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2].
  • Miranda HC; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3].
  • Frankowski H; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
  • Batlevi Y; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
  • Young JE; Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA.
  • Le A; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
  • Ivanov N; 1] Center on Human Development &Disability, University of Washington, Seattle, Washington, USA. [2] Department of Neurology, University of Washington, Seattle, Washington, USA.
  • Sopher BL; Department of Neurology, University of Washington, Seattle, Washington, USA.
  • Carromeu C; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.
  • Muotri AR; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Neurosciences, University of California, San Diego, La Jolla, California,
  • Garden GA; 1] Center on Human Development &Disability, University of Washington, Seattle, Washington, USA. [2] Department of Neurology, University of Washington, Seattle, Washington, USA.
  • La Spada AR; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Neurosciences, University of California, San Diego, La Jolla, California,
Nat Neurosci ; 17(9): 1180-9, 2014 Sep.
Article in En | MEDLINE | ID: mdl-25108912
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Autophagy / Receptors, Androgen / Muscular Disorders, Atrophic / Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2014 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Autophagy / Receptors, Androgen / Muscular Disorders, Atrophic / Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2014 Document type: Article Country of publication: United States