High frequency of bovine viral diarrhea virus type 2 in Southern Brazil.
Virus Res
; 191: 117-24, 2014 Oct 13.
Article
in En
| MEDLINE
| ID: mdl-25109547
ABSTRACT
Ruminant pestiviruses can infect cattle populations worldwide and cause significant economic losses due to their impact on productivity and health. Knowledge of pestivirus diversity is important for control programs and vaccine development and for determining probable sources of infection. In this paper, we describe a search for ruminant pestiviruses with RT-PCR in sera of 9078 calves from 6 to 12 months of age. The calves were first analyzed in pools and then analyzed individually. Thirty-three RT-PCR positive animals were detected (0.36%) from 6.9% (24) of the 346 herds. The sequencing analysis of the 5' non-coding region and N terminal autoprotease showed the presence of BVDV-1a (15 isolates), -1b (3), -1d (1) and -2b (14), with a higher frequency (42.4%) of BVDV-2 in comparison with other countries. The presence of sheep was significantly associated with BVDV infection. Our results also suggested that a BVDV control program based only on the investigation of cattle would not be successful, especially in regions with farms harboring multiple animal species. This study may also serve as a reference for future control programs in Southern Brazil because it reports the prevalence of cattle with active infections and the genetic background of the circulating strains.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bovine Virus Diarrhea-Mucosal Disease
/
Diarrhea Virus 2, Bovine Viral
Type of study:
Risk_factors_studies
Limits:
Animals
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Virus Res
Journal subject:
VIROLOGIA
Year:
2014
Document type:
Article
Affiliation country:
Brazil