Sequential ofatumumab and lenalidomide for the treatment of relapsed and refractory chronic lymphocytic leukemia and small lymphocytic lymphoma.

Costa, Luciano J; Fanning, Suzanne R; Stephenson, Joe; Afrin, Lawrence B; Kistner-Griffin, Emily; Bentz, Tricia A; Stuart, Robert K

Costa, Luciano J; Fanning, Suzanne R; Stephenson, Joe; Afrin, Lawrence B; Kistner-Griffin, Emily; Bentz, Tricia A; Stuart, Robert K.

Affiliation

Costa LJ; Division of Hematology and Oncology, Department of Medicine, Medical University of South Carolina , Charleston, SC , USA.

Leuk Lymphoma ; 56(3): 645-9, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25130476

Subject(s)

Antibodies, Monoclonal/therapeutic use; Immunologic Factors/therapeutic use; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy; Thalidomide/analogs & derivatives; Aged; Aged, 80 and over; Antibodies, Monoclonal/adverse effects; Antibodies, Monoclonal, Humanized; Drug Combinations; Drug Resistance, Neoplasm/drug effects; Female; Humans; Lenalidomide; Leukemia, Lymphocytic, Chronic, B-Cell/mortality; Leukemia, Lymphocytic, Chronic, B-Cell/pathology; Male; Middle Aged; Neoplasm Recurrence, Local/pathology; Neutropenia/chemically induced; Thalidomide/adverse effects; Thalidomide/therapeutic use; Thrombocytopenia/chemically induced; Treatment Outcome

Key words

Ofatumumab; chronic lymphocytic leukemia; clinical trial; lenalidomide; small lymphocytic lymphoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thalidomide / Leukemia, Lymphocytic, Chronic, B-Cell / Immunologic Factors / Antibodies, Monoclonal Type of study: Clinical_trials Limits: Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2015 Document type: Article Affiliation country: United States Country of publication: United States

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