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DNA methylation aberrations rather than polymorphisms of FZD3 gene increase the risk of spina bifida in a high-risk region for neural tube defects.
Shangguan, Shaofang; Wang, Li; Chang, Shaoyan; Lu, Xiaoling; Wang, Zhen; Wu, Lihua; Wang, Jianhua; Wang, Xiuwei; Guan, Zhen; Bao, Yihua; Zhao, Huizhi; Zou, Jizhen; Niu, Bo; Zhang, Ting.
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  • Shangguan S; Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China.
Birth Defects Res A Clin Mol Teratol ; 103(1): 37-44, 2015 Jan.
Article in En | MEDLINE | ID: mdl-25131656
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Spinal Dysraphism / Promoter Regions, Genetic / DNA Methylation / Polymorphism, Single Nucleotide / Frizzled Receptors / Neural Tube Defects Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Pregnancy Language: En Journal: Birth Defects Res A Clin Mol Teratol Year: 2015 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Spinal Dysraphism / Promoter Regions, Genetic / DNA Methylation / Polymorphism, Single Nucleotide / Frizzled Receptors / Neural Tube Defects Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Pregnancy Language: En Journal: Birth Defects Res A Clin Mol Teratol Year: 2015 Document type: Article Affiliation country: China Country of publication: United States