Prostaglandin E2 produced by inducible COX-2 and mPGES-1 promoting cancer cell proliferation in vitro and in vivo.

Ruan, Diana; So, Shui-Ping

Ruan, Diana; So, Shui-Ping.

Affiliation

Ruan D; I.I. Rabi Scholar Research Program, Columbia College, Columbia University, New York, NY 10027, USA.
So SP; Center for Experimental Therapeutics and Pharmacoinformatics, Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, TX 77204, USA. Electronic address: dtr2111@columbia.edu.

Life Sci ; 116(1): 43-50, 2014 Oct 22.

Article in En | MEDLINE | ID: mdl-25139833

Subject(s)

Cyclooxygenase 2/metabolism; Dinoprostone/biosynthesis; Inflammation/pathology; Intramolecular Oxidoreductases/metabolism; Animals; Cell Line, Tumor; Cell Proliferation/physiology; Colonic Neoplasms/pathology; Humans; Lung Neoplasms/pathology; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microsomes/metabolism; Prostaglandin-E Synthases; Prostatic Neoplasms/pathology; Receptors, Prostaglandin E/metabolism

Key words

Cancers; Cyclooxygenase; Inflammation; Microsomal PGE(2) synthase; PGE(2) receptor; Prostaglandin E(2) (PGE(2))

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dinoprostone / Intramolecular Oxidoreductases / Cyclooxygenase 2 / Inflammation Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Life Sci Year: 2014 Document type: Article Affiliation country: United States Country of publication: Netherlands

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