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Proinsulin-specific, HLA-DQ8, and HLA-DQ8-transdimer-restricted CD4+ T cells infiltrate islets in type 1 diabetes.
Pathiraja, Vimukthi; Kuehlich, Janine P; Campbell, Peter D; Krishnamurthy, Balasubramanian; Loudovaris, Thomas; Coates, P Toby H; Brodnicki, Thomas C; O'Connell, Philip J; Kedzierska, Katherine; Rodda, Christine; Bergman, Philip; Hill, Erin; Purcell, Anthony W; Dudek, Nadine L; Thomas, Helen E; Kay, Thomas W H; Mannering, Stuart I.
Affiliation
  • Pathiraja V; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
  • Kuehlich JP; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
  • Campbell PD; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
  • Krishnamurthy B; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia Department of Medicine, University of Melbourne, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
  • Loudovaris T; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia.
  • Coates PT; Department of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
  • Brodnicki TC; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia Department of Medicine, University of Melbourne, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
  • O'Connell PJ; National Pancreas Transplant Unit, University of Sydney at Westmead Hospital, Sydney, New South Wales, Australia.
  • Kedzierska K; Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.
  • Rodda C; University of Melbourne, NorthWest Academic Centre, Sunshine Hospital, St. Albans, Victoria, Australia.
  • Bergman P; Department of Paediatrics, Monash University, Clayton, Victoria, Australia.
  • Hill E; Department of Paediatrics, Monash University, Clayton, Victoria, Australia.
  • Purcell AW; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.
  • Dudek NL; Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.
  • Thomas HE; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia Department of Medicine, University of Melbourne, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
  • Kay TW; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia Department of Medicine, University of Melbourne, St. Vincent's Hospital, Fitzroy, Victoria, Australia.
  • Mannering SI; Immunology and Diabetes Unit, St. Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia Department of Medicine, University of Melbourne, St. Vincent's Hospital, Fitzroy, Victoria, Australia smannering@svi.edu.au.
Diabetes ; 64(1): 172-82, 2015 Jan.
Article in En | MEDLINE | ID: mdl-25157096
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proinsulin / CD4-Positive T-Lymphocytes / HLA-DQ Antigens / Islets of Langerhans / Diabetes Mellitus, Type 1 Limits: Humans Language: En Journal: Diabetes Year: 2015 Document type: Article Affiliation country: Australia Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proinsulin / CD4-Positive T-Lymphocytes / HLA-DQ Antigens / Islets of Langerhans / Diabetes Mellitus, Type 1 Limits: Humans Language: En Journal: Diabetes Year: 2015 Document type: Article Affiliation country: Australia Country of publication: United States