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p53 directly regulates the transcription of the human frataxin gene and its lack of regulation in tumor cells decreases the utilization of mitochondrial iron.
Shimizu, Rina; Lan, Nguyen Ngoc; Tai, Tran Tien; Adachi, Yuka; Kawazoe, Asako; Mu, Anfeng; Taketani, Shigeru.
Affiliation
  • Shimizu R; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.
  • Lan NN; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.
  • Tai TT; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.
  • Adachi Y; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.
  • Kawazoe A; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.
  • Mu A; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan.
  • Taketani S; Department of Biotechnology, Kyoto Institute of Technology, Kyoto 606-8585, Japan; Insect Biomedical Center, Kyoto Institute of Technology, Kyoto 606-8585, Japan. Electronic address: taketani@kit.ac.jp.
Gene ; 551(1): 79-85, 2014 Nov 01.
Article in En | MEDLINE | ID: mdl-25158131
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genes, p53 / Iron-Binding Proteins / Iron / Mitochondria Limits: Humans Language: En Journal: Gene Year: 2014 Document type: Article Affiliation country: Japan Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genes, p53 / Iron-Binding Proteins / Iron / Mitochondria Limits: Humans Language: En Journal: Gene Year: 2014 Document type: Article Affiliation country: Japan Country of publication: Netherlands