Your browser doesn't support javascript.
loading
H1N1 triggered recurrent acute necrotizing encephalopathy in a family with a T653I mutation in the RANBP2 gene.
Anand, Geetha; Visagan, Ravindran; Chandratre, Saleel; Segal, Shelley; Nemeth, Andrea H; Squier, Waney; Sheerin, Fintan; Neilson, Derek; Jayawant, Sandeep.
Affiliation
  • Anand G; From the *Department of Paediatric Neurology; †Paediatric Infectious Disease and Immunology, John Radcliffe Hospital; ‡Department of Clinical Genetics, Churchill Hospital, Oxford University Hospitals NHS Trust; §Department of Clinical Neurosciences, University of Oxford; ¶Department of Neuropathology; ‖Department of Neuroradiology, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxfordshire, United Kingdom; and **Division of Human Genetics, Cincinnati Children's Hospital Medical
Pediatr Infect Dis J ; 34(3): 318-20, 2015 Mar.
Article in En | MEDLINE | ID: mdl-25170550
A 28-month-old infant presented with fever, vomiting and encephalopathy. Magnetic resonance imaging findings and family history confirmed a diagnosis of recurrent familial acute necrotizing encephalopathy (ANE1). We believe that this is the first description implicating the H1N1 viral strain as a trigger and the second report of a T653I mutation in the RANBP2 gene described in relation to ANE1.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Chaperones / Leukoencephalitis, Acute Hemorrhagic / Amino Acid Substitution / Nuclear Pore Complex Proteins / Influenza, Human / Influenza A Virus, H1N1 Subtype / Mutation Limits: Adult / Female / Humans Language: En Journal: Pediatr Infect Dis J Journal subject: DOENCAS TRANSMISSIVEIS / PEDIATRIA Year: 2015 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Molecular Chaperones / Leukoencephalitis, Acute Hemorrhagic / Amino Acid Substitution / Nuclear Pore Complex Proteins / Influenza, Human / Influenza A Virus, H1N1 Subtype / Mutation Limits: Adult / Female / Humans Language: En Journal: Pediatr Infect Dis J Journal subject: DOENCAS TRANSMISSIVEIS / PEDIATRIA Year: 2015 Document type: Article Country of publication: United States