Cationic surface charge enhances early regional deposition of liposomes after intracarotid injection.

Joshi, Shailendra; Singh-Moon, Rajinder; Wang, Mei; Chaudhuri, Durba B; Ellis, Jason A; Bruce, Jeffrey N; Bigio, Irving J; Straubinger, Robert M

Joshi, Shailendra; Singh-Moon, Rajinder; Wang, Mei; Chaudhuri, Durba B; Ellis, Jason A; Bruce, Jeffrey N; Bigio, Irving J; Straubinger, Robert M.

Affiliation

Joshi S; Department of Anesthesiology, College of Physicians and Surgeons of Columbia University, New York, NY, 10032, USA, sj121@columbia.edu.

J Neurooncol ; 120(3): 489-97, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25195130

Subject(s)

Brain/metabolism; Cations/chemistry; Drug Delivery Systems/methods; Injections, Intra-Arterial/methods; Liposomes/administration & dosage; Liposomes/chemistry; Animals; Blood-Brain Barrier/diagnostic imaging; Blood-Brain Barrier/metabolism; Brain/drug effects; Brain Neoplasms/drug therapy; Brain Neoplasms/metabolism; Capillary Permeability/physiology; Carbocyanines/administration & dosage; Carbocyanines/chemistry; Cell Line, Tumor; Feasibility Studies; Liposomes/pharmacokinetics; Male; Nanoparticles/administration & dosage; Nanoparticles/chemistry; Neoplasm Transplantation; Optical Imaging; Rats, Sprague-Dawley; Spectrum Analysis; Ultrasonography/methods

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Cations / Drug Delivery Systems / Injections, Intra-Arterial / Liposomes Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Neurooncol Year: 2014 Document type: Article Country of publication: United States

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