A fusion DNA vaccine encoding middle version of HBV envelope protein fused to interleukin-21 did not enhance HBV-specific immune response in mice.

Zhang, Ye; Su, Wen-Jing; Wang, Jue; Bai, Xue-Fan; Huang, Chang-Xing; Lian, Jian-Qi

Zhang, Ye; Su, Wen-Jing; Wang, Jue; Bai, Xue-Fan; Huang, Chang-Xing; Lian, Jian-Qi.

Affiliation

Zhang Y; 1 Center for Infectious Diseases, Tangdu Hospital, Fourth Military Medical University , Xi'an, China .

Viral Immunol ; 27(9): 430-7, 2014 Nov.

Article in En | MEDLINE | ID: mdl-25211639

Subject(s)

Hepatitis B Vaccines/immunology; Hepatitis B/prevention & control; Interleukins/immunology; Vaccines, DNA/immunology; Viral Envelope Proteins/immunology; Animals; CD8-Positive T-Lymphocytes/immunology; Hepatitis Antibodies/blood; Hepatitis B Vaccines/administration & dosage; Hepatitis B Vaccines/genetics; Interleukins/genetics; Male; Mice, Inbred BALB C; Mice, Transgenic; Plasmids/administration & dosage; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/immunology; Vaccines, DNA/administration & dosage; Vaccines, DNA/genetics; Vaccines, Synthetic/administration & dosage; Vaccines, Synthetic/genetics; Vaccines, Synthetic/immunology; Viral Envelope Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Envelope Proteins / Interleukins / Hepatitis B Vaccines / Vaccines, DNA / Hepatitis B Limits: Animals Language: En Journal: Viral Immunol Journal subject: ALERGIA E IMUNOLOGIA / VIROLOGIA Year: 2014 Document type: Article Affiliation country: China

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